Most comfortable bike I have ridden is my Jamis Aragon. It is an aluminum frame city bike with spring post seat tube and a great coil spring seat. The handlebar stem is a spring type so the whole thing has most of the advantages of a full suspension without the weight. Two modifications added to the mix are bar end handles moved inboard five inches either side if the stem and a layer of neoprene foam rubber on the hand grips and handles. With my weight balanced between hands and seat there is no excesive pressure. Vision is good and my lungs are not restricted. The "hands together" grips give a slight aero improvement. The next step is to design a practical aerobody from shoulder to knees.
The Audi bike looks cool and comfort will have to bee seen. The most comfortable bike I have ridden is a Cervelo S3 which absorbs the shocks very well considering the lack of suspension.
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2 cars one never gets driven the other is an MPG project already at 5% increase in standard driving economy CAI and Pulstar plus. Thinking weight reduction next year.