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Nay, the octane boosters add 1/10th of an Octane aka a point. And the size is negligible to a fuel tank with several gallons. Some of the Street/Racers use Xylene to boost octane. But it is much more expensive than gasoline. Older engines have carbon buildup so switching to a higher octane will help with aging problems but the only way to fix it is to get the engine cleaned, the most common method is to use something like seafoam.
Advancing the timing and moving up on octane has been done before. The benefits are a wash, it can give better MPG but rarely does it compensate for the higher cost. If it does increase MPG Your Mileage will Vary and it differs based on the engine.
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~Allch Chcar
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