On both of my Hondas - a 96 civic 1.6 and a 2004 Odyssey 3.5 - the best mileage comes below 2,000 rpm. Basically, lower rpm is better, so long as you're not flooring it just to keep moving. Three-quarter throttle and something below 2k rpm is great.
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11-mile commute: 100 mpg - - - Tank: 90.2 mpg / 1191 miles
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