Here's something that will help some of you understand what it is I'm asking, exactly.
This is how a traditional Otto-cycle 4 cylinder works, the firing order of this engine would be 1,3,4,2.
If you want to properly envision what would be going on with each scenario I posted, just stick your finger over the missing piston from my description and watch the rest of the engine. Notice where the #1 and #4 crank weights are in relation to the #2 and #3 cylinders.
I do think I might be able to alleviate some of the problem with the crank weights by either weighting the journals with something similar to the weight of the piston/rod assembly, or by removing weight from the counter weights on those throws.
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"¿ʞɐǝɹɟ ɐ ǝɹ,noʎ uǝɥʍ 'ʇı ʇ,usı 'ʎlǝuol s,ʇı"