[PaleMelanesian]

Having replaced a set of Michelins (symmetry, decent LRR tires themselves) with a new set of Fuel Max tires, I'll say the following:

The Fuel Max are quieter and a smoother ride.
The Fuel Max at 44 psi were much softer-feeling than the Michelins. Going up to 51 psi brought back the solid feel I was expecting.
I've seen about 1 mpg improvement (23 vs 22) in the Odyssey.

You're getting 46 mpg. Just for comparison, let's say the FuelMax will match that and the Michelins will get 48 mpg. Over a 60,000 mile lifetime, that's worth about 54 gallons, or $150 at 2.75/gallon. 4 of the Michelins will cost $128 more than the FuelMax's, so you'd actually be ahead from the fuel savings.

If you count only a 1 mpg increase, it's $75 savings, or a slight loss overall. Still, I'd probably go with the Michelins.

I'd rather spend money on tires than on fuel, considering the nationalities of the two sources.