I don't think it mater much for mpg but the manufactures want the cat and O2 to get heated as fast as possible . My 08 Accord the O2 is like 6" from head but thats because there is no header manifold and the cat is like only 12" max from head .
Most turbo cars have O2 in the down pipe within a ft , many are inches from turbo but have not checked with vehicles with WB O2 .
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