Question - are you looking for lightest weight or best FE ? Or are you just wanting a bike engined Imp (deep respect
) with some FE ?
The best FE would be the ForTwo diesel or the 1.2 Polo TDi. Good luck on the latter one. And If you do those then either go mid-engined or line yourself up with a load of work to get a suitable gearbox and gearing unless you can get the gearbox from the Smart to fit.
Reasonable FE would be a more modern car engine, say a K-Series maybe a 1.1i with FI to take advantage of EOC etc. But then you have to connect it to your transaxle but this has been done.
The Imp is of course a small cottage for Aero unless you work on it quite hard. There are a few Clans about which you could use for this type of conversion which have less frontal area but may need Aero work.
Hillman Imp (god, what did Chrysler think when they bought Rootes ?)
Slightly more sporty Imp Coupe
Clan Coupe (Imp oily bits)
Note the best car ever in the background...