Diesels are a whole other ball game when it comes to their set up. As a Ford tech I always played dumb on them, I wasn't going to be the only one poising my shirt on warranty work that didn't pay.
Usually mods to the motor increase power and economy to a diesel, unless set up to huge powergains. Blowing soot is not efficient combustion but huge gains in power.
For economy on the truck I would try lower gears unless you tow with it. If 4x4 take the drive shaft out unless 4x4 is necessary.
Try a centane booster from advance or some store, add it to a tank of fuel and see if it makes a difference. Recently the Govt mandated a lower sulfur content for diesels and every truck produced before the mandate has lost power and economy (diesels of course).
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