I think they compensate by having slightly heavier fly wheels, with a v6 or 8v engine you kill half the cylinders so the firing is still balanced just less often, with the Honda civic hybrid they kill 3 of the 4 cylinders and close the valves of the dead cylinders then use the motor that is part of the fly wheel, to even out the firing so it runs smoothly, the closed valves alow the o2 sensor to work properly.
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