Filled up yesterday. This was a tank to Asheville and up (and down) the Old Fort Grade. Again the scangauge was off, it was reporting 40.6 and my calculations was 38.25, an almost 6% difference. Normally I don't see much over 0.5 MPG (+/- 1-2%) difference between the scangauge and actual.
I don't think anything is wrong with the scangauge, I just think the car is actually burning fuel when it is reporting that it isn't. I was just wanting to know if anyone else had ran into a similar issue. Thanks to everyone for the read and the advice.