My own personal guess is that if you are driving in an MPG-conscious manner, the difference between the stock exhaust and the one pictured would be minimal. With one exception:
The O2 sensor.
If you can have someone weld an O2 sensor bung onto the header some appropriate place (there are arguments for specific distances from the exhaust valve, or in the common collector, and probably arguments for elsewhere too!) and hook up a sensor correctly, you'll do better.
If you can't do that, or if it's too tough to figure out where "some appropriate place" is, then going back to the original manifold and hooking up the O2 sensor correctly will give you better economy than the current setup.
Regardless of either, a decent muffler will make your neighbors hate you a lot less...
-soD
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