The way you and I are running these trucks -- low-rpm, low-load -- there will be some carbon build-up at the injector tips and in the combustion chambers. A cleaner is going to help this problem somewhat. I'd still rather run it hard to redline once a month or so, maybe in Third, but definitely in Fourth and Direct.
So, I'd say sacrifice a bit of fuel in some hard runs. Maybe: fill, run hard 50-miles (loaded, towing?), and refill. We'll none of us notice that 3-4 gallons didn't make it onto the fuel log.
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