I would say some of the more enclosed designs do present additional safety concerns, just for the fact that the rider can't easily get separated from them (like a conventional cycle) in a crash.
Last thing you want is to be held-in or get tangled-up with a cycle (or anything without a cage of some kind) when you crash.
Enlarged windshields that protrude high and back could also cause injury in the event of even a slight front-end collision.
Jay
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