Right- the hitch mechanisms are different. But they both go to the center of the pickup box and they'd both be dealt with in identical or at least similar fashion from the standpoint of bedcovers and tailgates or whatever.
Anyway, back to OP's question, seems to me a lot of interaction there and I wouldn't want to make any bold predictions, but I'm pretty sure the "rolling wave" thing that naked pickups have going in the box wouldn't be the case here at all. Seems intuitive that a bed cover would help...
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