I don't know what kind of annual mileage your wife is going to be doing with the car...
But it's worth considering fuel costs very carefully: 12,000 miles/year, 5 years, 13 MPG difference between a CX-5 and a Prius v: you'll save 640 gallons, say at 3.50$ that's 2200$.
That works to reduce (unfortunately not eliminate) the price premium for the hybrid...
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