Just to throw my anecdote in here, I've been running a stock MY2002 Grand Cherokee Overland (4.7L "high output" engine) on E85 for ~4500 miles so far, with no ill effects apparent. It doesn't appear to run out of fuel bandwidth at WOT/onramp merging/hills, and doesn't illuminate the check engine light.
Plus it smells a bit like vodka when I cold start & then reverse into my exhaust cloud. Maybe I should throw a few lime peels into the tailpipe...
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Work From Home mod has saved more fuel than everything else put together.
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