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Biodiesel is aggressive and will destroy seals, hoses etc. I once had my fuel lines destroyed within a single tank...
However, there are materials that can cope with biodiesel. If you're lucky, your car is equipped with those. If you're not, then you have to replace fuel hoses and seals in the injection system with their more resistant counterparts (look for "fluoro rubber", "fluoro caoutchouc" or the trade name "viton").
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