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Hi, new guy here. ASE Master tech (14 years)
A few things of note:
Stock rubber auto tire (snap-in style) valves are only rated to handle around 45 psi max. Higher pressure tires use different, bolt-in stems. It's unlikely you'll eject a stem at 50 psi but it is worth considering, if you run at max pressure all the time - particularly in hot weather and high speed freeway driving where heat build up will be the most noticeable.
Tires inflated to the sidewall max will run cooler but may not last longer because of premature center channel treadwear due to carcass distortion, and faster sidewall and tread cracking from pressure stress. Think of a balloon - inflated to the max it is highly stressed, relative to the stress level @ 50% inflation. Fatigue cracking in the rubber is faster in tires left inflated to 100% max all the time.
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