In a 205/65/16 you have the option for the Energy Saver A/S. I have yet to find a more fuel efficient tire. I'm seeing a 3mpg gain vs. the OE AVID S33D and AVID Ascend. TireRack also observed a 3mpg gain over other LRR and one non- LRR tire.
When Round and Black Becomes Lean and Green
They are not the best for handling, however.