That 350ci reverse trike would be a great starter idea for a MPG build. Instead of a Toronado V8, use a Metro 1.0L. Stretch the frame back another 18" so you sit down in front of the rear wheel instead of over it, get out of the air flow. And I don't know about a single-sided swingarm, that sounds dangerous in a 2F1R.
Good video, makes my mind wander