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GMO are done so that companies like Monsanto can make big profits. We already have a number of "super weeds" that are now immune to Roundup, just like the GMO seeds, so what's the point? Why should we risk our health for such a short term gain? It is almost a guarantee that if we mess with things, it will do damage.
Getting that crap into the water system is definitely messing things up. Have you seen the amount of plastic and chemicals in the food chain? Blinky the fish is pretty much what we have already. I wouldn't eat seafood from the Gulf of Mexico if you paid me - the dead zone from the Mississippi is only part of it...
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