I don't have an MPGuino for either of my cars (yet), but I do have vacuum gauges fitted to both and will be keeping those vacuum gauges when I do get MPGuinos. I think the two should complement each other nicely.
Neither car is OBD2, so I can't use a scangauge or similar to get engine load % readings for the pulse of P&G.
Taking full vacuum (idle) as no load and zero vacuum as full load, I can guestimate the 80% engine load that's usually recommended for pulses.
I treat pulses the same for both auto and manual, it's the glide that's different.
I also use the vacuum gauge readings when climbing hills for DWL.