Hey Slowmover,
Thanks for all the useful advice and pointers
My thought for this was to build a scratchbuilt RV from the ground up. This way I could tailor it exactly for not only our needs but for best fuel economy and comfort as well.
We would use it to travel the entire North America and most likely down to the Panama Canal! Who knows we may also venture into South America with it as well.
Since we would be spending a lot of time in it we would need it to be fully established so bathroom, kitchen, living area would most likely be preferred. I know this is what my wife would want so if I am going to do it I would like to make her happy and comfortable.