Think you are missing the point of how gas engines operate, 90% of the time the intake manifold is at negative pressure, that's the nature of the beast, so there is nothing to bleed off and engine already controls how much fuel and air goes in, so any other restriction further back just results in the same outcome.
Pumping losses are a misnomer, the greatest loss is in the Induction stroke, so they should really be called sucking losses and this is the main reason why diesels are more efficient as they are designed to run with excess air, hence do not have a throttle, so minimal sucking losses.
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