I've run studded tires for years on the rear only. With adequate weight for traction, they will get through most everything. They really help with engine-braking too, which is important on snow and ice. Of course, the weather conditions that require studs will naturally hit FE a lot more than the smaller tire diameter will.
On dry or clean pavement, I imagine that having studs on the front might actually hurt performance. They will certainly change the steering dynamics, especially at higher speeds...
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