I don't recall seeing direct comparison testing of this before, but I'll agree with the others; it's probably not a big difference, but it's probably a lot easier to get a more air-tight seal in front of the grill than behind (or even better, flush with the outermost bodywork).
I prefer in front, both for ease of construction and air-seal reasons. (I also am fine with drilling holes in plastic bodywork and having sheet metal and screws/rivets visible on my car; looks are not a high priority for me).
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