I run iridiums as well. I doubt they do much for fuel economy, but they last a looong time. They are usually cheaper simply because they can outlast 5-6 sets of copper plugs.
My old man has a spark plug cleaner from Harbor Freight, and he pulls his iridiums at 50k and 100k miles to clean and regap. He says he usually get 150k from each set of plugs. I'm lazy, and just toss mine at 90-110k and replace.
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