I rent 26' box trucks from penske on the daily for long distance and local for my moving company.
If I'm doing a long trip the first stop I make I go and check all the tire pressures.
I get like 9 MPG on a trip to Florida or Tennessee and back to Maryland half full half empty.
They all have 6 speed automatics and run on diesel.
They are governed at 70 MPH and lose alot of power going uphill even empty.
I don't make any effort to get better mileage or hyper-mile the only reason I check the tires is so I wont have a blow out. Customer pays for fuel. They can fit a entire house of things and stuffs so I think 9MPG is amazing.