FWIW I had the long, tall Sprinter van (2004) that was a cargo van with a minimal conversion. The lifetime mileage was just under 25mpg, usually holding it between 60 and 65 on the freeway; and toward the end when it was broken in (80k miles) I was averaging 27mpg. There were no aero mods other than removing one of the windshield wipers and substituting reflective tape for the plastic reflectors. I could carry a 16 foot piece of lumber if it went between the front seats (never mind the plywood).
The bad news is that it was pretty loud on the road. I got tinnitus from driving that thing.
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