You are right, in reality it's really hard to isolate all the variables. In practice the choice for my car is between: 175/65 R14 H, 185/60 R14 H and 195/50 R15 V. Currently I have the latter, which is best for handling.
I read it on your site and it is interesting to me that high speed rated tires tend to have higher rolling resistance coefficients. I was hoping that by deflecting less they would roll better.
The same could be said for side wall size. I was hoping a short side wall would help, but your regression shows the opposite.
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