I don't see any reason why it shouldn't work in principle. After all, centrifuge enrichment of uranium hexafluoride gas is one way to separate the fissionable U-235 from the U-238. Whether the production rate would be high enough to be useful is another question.
One drawback, though, is that the enriched gas is going to contain a lot more argon and CO2, because they're heavier than oxygen.
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