The question of tire life is moot for me. I got 31,000 miles on one front and two rear tires on my CBR250R. And one thing I can say for the Pilot Street bias tires that come on the R3 is that they are very low rolling resistance. I thought I had noticed this when I put the Bridgestone S20 evos in their place and my fuel economy on the R3 went down. Then when it was time to replace the IRC Roadwinners on my CBR250R commuter bike after 15,000 miles rear/ 31,000 miles front, I got another 10% improvement in fuel economy. I hope they last longer too. Some endurance riders on the Ninjette forum are getting 20,000 miles on a rear with the Michelins.
.
Honda CBR250R FI Single (Honda CBR250R) | Fuelly
.