Good food for thought.
I have a diesel Excursion that I use pretty much exclusively for work (hauling supplies and parts internally, or pulling a 24'x8.5' enclosed trailer). It gets nearly 25 mpg at 55, but only about half that pulling the trailer. I drive it about 10,000 miles a year, but those tend to be longish (300-4000 miles) trips at highway speeds where it would benefit the most from even modest aero mods.
I gotta put some thought into this.
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Best tank ever: 72.1 mpg in February 2005, Seattle to S.F.
New personnal best 'all-city' tank June '08 ... 61.9 mpg!
Thanks to 'pulse-n-glide' technique.