I think there might be structural problems. With the plane, the loads of the main landing gear are carried by the wing's main spar. Almost all the weight is carried on the mains, very little on the nose wheel. (A reasonably strong person can lift the nose wheel off the ground - that's how I change the tire :-)) So I think it'd be hard to re-do the structure to handle highway wheel loads and have decent balance. Probably easier to start from scratch.
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