As has been pointed out, there are a lot of variables.
In fact, I looked at tire rolling resistance here:
Barry's Tire Tech - Rolling Resistance and Fuel Economy
With a followup here:
Followup an Rolling Resistance and Fuel Economy
Bottom line:
All other things being equal, a wider tire is better for rolling resistance - and it is likely that it will still be better overall - including aerodynamics, because tires are typically surrounded by the car body and only a small portion is exposed to oncoming air.
The biggest problem is that very rarely are all things equal. Proper selection of a tire can pay dividends in fuel economy.