I could see it. The prius is only slightly more aerodynamic that the corvette with similar frontal area. Per Stanford the car reaches ~36% peak thermal efficiency at 2000 rpm. (think air pump n chart g/kWh).
If you could do it similar to the prius, boats, or airplanes, and have it tuned to have max efficiency at a x speed you could really take advantage of it.
Also, an interesting note about afr per NASA from 1930 ish on airplanes:
"with gasoline as a fuel, maximum power is obtained with fuel-air mixtures from 0.07 to 0.08 pound of fuel per pound of air; (3) nearly minimum specific fuel consumption is secured by decreasing the fuel content of the charge until the power is 95 per cent of its maximum value. Presumably this information is of most direct value to the carburetor engineer."
https://ntrs.nasa.gov/archive/nasa/c...9930091255.pdf
So basically tune the car to run at 2000 rpm at 70 mph at around 75-92% load and then lean it out.
I'd probably add that its centered from 1500-2000 RPM at almost the same efficiency.
I had a guy stay in my airbnb recently and he showed me his gm hp tuners on his laptop. From what I saw with that and it showing VE tables, and BSFC at each value I honestly think its doable. Also, you could then just delete the cats and delete the cat enrichment warmup process.