The result, as you say is probably buried in the noise.
I would be weary of opening the cabin into the wake. Carbon Monoxide.
I can imagine a duct on the A-pillar might effectuate an air curtain over the opening. The only thing I've seen like that would be the Mercedes-Benz Air Cap:
coolhunting.com/tech/mercedes-benz-a/
Those plastic deflectors might be a good base, cut slots and cover them with mesh.