I had to look up Plex. As long as the client[s] is/are multiuser, I think that's an on label use.
Does it have an NPU? The only use I can think of for one for me would be graphic inpainting and outpainting. I've got a lot of old low-res pictures from the 1990s.
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If it doesn't it's zero-day obsolete. (Don't be embarrassed, I'm way back on the curve -- the PI 5 can only do 12-24 TOPS)
AMD Ryzen NPU does 30-50 TOPS. Free business loaners now according to this video's ad:
In-memory logic means the CPU-RAM bottleneck goes away, with orders magnitude less power consumption.