Buckminster Fuller's buckyballs and domes are not in fact compound curves but a collection of flat surfaces no good for aero, which is why I lose interest here.
As far as buildings go; rectangular shapes are far easier/cheaper to construct, so I/we are at a bit of a loss as to your predilection for them?
I have a predilection for the 60 atom carbon molecule (C60 BuckyBall) because, dissolved in olive oil (C60 OO), it doubled the life/youth-span of lab rats with not a single cancer cell in sight.
Aaaand there 99.999% of any readers go..!
Science; a thankless job and copy-paste-google an impossibility it seems...