drcoopster, I don't want to be disagreeable but for very large airports near large metropolitan areas, I think they tend to have preferred directions based on normal prevailing winds and desired noise reduction strategies and will often let themselves get into very mild downwind landing situations so that they don't have to reverse patterns, or annoy residential neighbors. In addition, they can also permit crosswind situations that would be treacherous for small aircraft if all they have landing there are large commercial jets.
On small airports, or airports with mixed general aviation, the wind totally rules.
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