I remember cylinder deactivation on my brothers old '89 bronco... lol idled great, revved great, but couldn't move the truck in 1st gear over a 3" bump on the dirt pad. Took us forever to figure it out, entire left bank was unplugged :P We were amazed it sounded so normal and ran at all.
I see no reason why you couldn't drop 4cyl on highway cruising. It only takes a micro second to fire up the down cyl's when the power is needed. I know my dad doesn't need all 496 ci for driving to work. Hell, that truck would drive fine with 6 cyl 90% of the time. It doesn't need all 320hp and 480ft-lbs on tap, only when pulling or climbing.
Someone should get aggressive with the cyl deactivation, and see if you can daily a 1/2T or 3/4T on 6 or even 4 cyl. That'd amaze me more than squeezing more hp/ci.
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