IIRC, my 1998 HitchHiker 5th wheel had regular "E" tires on them, non-ST. I actually used my F250 spare tire/wheel which fit perfect when I had a flat. I bought all new tires for it 235/85/16E. You about can't get ST tires for big 5th wheels these days.
In a pinch, I suppose you could temporarily use trailer tires, but only if you treated them like 55 mph donut spares. On the contrary though lots of people drive their 5th wheels with ST tires at 75 mph, take the turns like sports cars and never have a problem. Usually the STs have pretty stiff sidewalls, so handling would be a touch "funny". Tread patterns on trailer tires vary so much these days they almost look like all-terrains. Overall, tough call.
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