It really depends on how you live. I live about an hour from the city, for a variety of reasons. I work in that city, though, so I go there everyday. I can pickup my items on the way back from the office, and be done. For me, it doesn't make a difference.
If you work from home or close to it, and are pretty good at planning, I could see the appeal of shopping via amazon for common things. No gas, no lost time; basically, the mountain comes to you.
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