There has been some information posted stating that wider tires have a lower coefficient of rolling resistance (i.e., lower rolling resistance than their narrower counterparts), but I'm not sure how that translates into real world mpg. Your mileage is affected by aerodynamics more than rolling resistance, so having a wider tire might still cost you mileage despite the decrease rolling resistance.
That being said, the composition of the tire is more important, and M/S and summer tires are probably equally bad on mileage. Most of the good LRR tires are A/S. Also, if the tires are taller, you'll gain a few % just based on fewer rotations per distance traveled.
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