Your mods will probably help, but not a whole lot,
which is to say it may not be measurable.
In total the wheel well and tire contribution to Cd for all four
wheels and wells is ~0.09. You might decrease that by 0.005
if you're lucky, which would mean gas savings out in the 3rd
decimal place of MPGs.
Then again, if it ain't hurtin' the numbers, why not give it
a go.
