I seem to remember seeing that error code and I got past it somehow. In your device manager, make sure that when your Arduino is plugged in, you have a device called "Arduino UNO R3 (COM3)" under "Ports (COM & LPT)". If not you may need to install the drivers which are in the arduino folder.
In the Arduino program please check the following: under Tools->Board have "Arduino UNO" and Tools->Port "COM3" (unless yours is COM1) selected.