Based on my 2002 suburban after 50,000 miles of mixed E10 & E85 use, I'd expect 15% loss in mpg IIRC 15 down to 12.5 (data on fuelly.com) 2010 Impala not as much data but leaning the same.
My new Cobalt isn't FFV, but newer HHR's are with same engine, I'm going to run the part numbers and see what's different. After I get a good baseline with E0 & E10.
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