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In my car it has not had any negative effects. 30,000+ miles covered and when i get new tire last month they said the OEM breaks had 1/3 life left. now I do not use the breaks much but when I do I am ok.
The issue is long term heat build up. are you racing to stops? start then stopping several times in a 3-5 min period? are you towing? even in the mountains I was ok, they got warm but held and worked fine. in 95% of hypermiling driving you will be ok.
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