As your mileage gets higher it's going to be harder to improve.
I would say 100mpg is perhaps a bit lofty of a goal, but with a 75mpg tank maybe 85 would be a good one to shoot for. You might need an engine swap and roof chop to get 100!
If I were you I'd rebuild the boat tail with some generous radii to reduce pressure differentials that form vortexes. Could you radius it enough that the rear end looks like an oval (airplane fuselage)? Something like 3-Wheeler did, but glass the outside, and use that as a mold for the final piece. That way it won't be so heavy. Might get you 3-5mpg or so depending on its current performance?
Also, gap sealers at the seam between the car and boat tail. LRR tires. Maybe some weight reduction- racing wheels, carbon hood, lexan rear windows. Not sure if any companies actually make Matrix racing parts.
Yikes. $400
http://www.ebay.com/itm/03-04-05-06-...5ba004&vxp=mtr
----------------------------------
On my MPG front, I am really wanting a pitot tube (one that looks vaguely aerospace-like if possible). Driving the Rabbit yesterday I found a sweet spot to the rear side of a box truck; it felt like there was no wind at all! Having a means of determining wind speed in the aeromodded car could pay dividends.