A pair of gauges would help. In the Cummins world it's the 666 Rule:
600F or less on exhaust gas temperature (EGT)
60-mph or lower in top travel speed
6-psi on manifold pressure (BOOST)
Big Dave and Jacob Aziza are both contributors with IH-motored Fords worth reading.
As to business use, be sure to plan each trip as well as possible. Mapquest has an option of re-ordering stops for best time/economy (as with the practice of FED-EX and UPS).
I'd pre-heat the fluids to shorten warm-up time as much as possible. Never idle and never stop (learn to drive all over again is the fair way to put it to your self).
Tires are big: commercial service highway rib (closed shoulder) as with BRIDGESTONE Duravis m500 when the time comes (or, r700). Alignment, brake drag and steering wander deserve your attention.
Someone will mention trans swap to ZF-6, but an auto is easier to live with when quite heavy in metro traffic (short periods at target travel speed versus the long periods on highways).
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